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Useful Resources

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Useful Scientific Resources

  • Bioinformatics

    AlphaFold
    biomolecular structure predictions
    antiSMASH
    antibiotics & secondary metabolite analysis shell
    Batch Entrez
    retrieves large numbers of NCBI records
    BLAST
    finds regions of similarity between biological sequences
    CASTpFold
    tool for determining protein topology
    Consurf
    identifies conserved residues in homologous proteins
    EFI – Enzyme Similarity Tool
    tool for generation of sequence similarity networks
    HMMER
    EMBL-EBI search tools using profile hidden Markov Models
    HHPred
    secondary structure homology prediction
    Integrated Microbial Genomics (IMG)
    analysis, annotation, and distrubtion of microbial genome datasets
    InterPro
    functional analysis of proteins by classification into familes, predicting domains and important sites
    MicroScope
    a web-based platform for comparative microbial genome analysis and manual annotation
    MUSCLE
    multiple sequence alignment creation
    RADAR
    repeat detection in proteins
    RadicalSAM.org
    RadicalSAM.org enables the use of the EFI’s genomic enzymology web tools for studies of the radical SAM superfamily
    Regular expression cheat sheet
    reference tables for basic regex
    RODEO
    algorithm for the analysis of biosynthetic gene clusters, with an emphasis on RiPPs
    SignalP
    signal peptide prediction
    Skylign
    logo creation
    STRING
    database of known and predicted protein interactions

  • Microbiology

    ARS Culture (NRRL) Collection
    searchable online catalog of the NRRL collection of microorganisms
    ATCC
    nonprofit, global biological resource center and supplier of authenticated cells lines and microorganisms
    DSMZ
    Leibniz Institute strain collection

  • Molecular biology

    Codon Usage Database
    list of codon usage for different organisms
    Expasy-ProtParam
    computation of various physical and chemical parameters for a given protein
    Expasy-Translate
    translation of a nucleotide sequence to a protein sequence
    IDT OligoAnalyzer
    calculates properties of oligonucleotides
    JCat
    Java-based codon adaptation tool
    NEB Cloning and Synthetic Biology Tools
    NEB tools for molecular cloning, DNA assembly and synthetic biology
    NEB Tools and Resources
    interactive tools from NEB for research and experimental design
    Protein Data Bank
    repository of information about the 3D structures of large biological molecules, including proteins and nucleic acids
    Sequence Manipulation Suite
    compiled list of JavaScript programs for generating, formatting and analyzing DNA and protein sequences

  • Reference Databases

    BRENDA
    Comprehensive Enzyme Information System
    Dictionary of Natural Products
    structure and biological origin of natural products
    MEROPS
    information resource for peptidases and the proteins that inhibit them
    MIBiG
    database of biosynthetic gene clusters
    PubChem
    information on the biological activities of small molecules
    PubMed
    free database accessing primarily the MEDLINE database of references and abstracts on life sciences and biomedical topics
    SciFinder
    CAS database of chemical and bibliographic information

  • Spectroscopy

    ChemCalc Molecular Formula Finder
    generate a list of molecular formulas from an accurate mass
    Dinesh NMR
    peptide NMR tools, including Random coil Proton Chemical shifts
    Interactive Peptide Spectral Annotator
    analysis of MS/MS data
    ProteinProspector
    proteomics tools for mining sequence databases in conjunction with mass spectrometry experiments
    RESID Database
    database of known protein modifications
    Unimod
    protein modifications for mass spectrometry

Safety Resources

Environmental Health and Safety (EHS)

Fire Extinguisher Training
guide to fire extinguisher types and fire types
NIOSH Pocket Guide to Chemical Hazards
key hazard information on specific chemicals, including properties and toxicity information
Prudent Practices in the Laboratory
publication (free online as e-book) from the National Research Council including extensive safety practices on use of reagents and equipment as well as chemical disposal
Safety in Academic Chemistry Laboratories
brief electronic publication (pdf e-book) by ACS with general practices for specific laboratory techniques
Vanderbilt Biological Safety
Vanderbilt Chemical Safety and Waste disposal

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