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Magnuson Lab

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RECENT PUBLICATIONS:
In Diabetes, Osipovich et al. describe studies exploring the Ca2+-dependent transcriptional dynamics of freshly isolated pancreatic islets.  Their findings establish a close temporal link between membrane depolarization, changes in intracellular Ca2+ concentrations, alterations in the islet transcriptome, and impairments of β-cell identity and function.

Sites of Sox17 expression in a developing mouse embryo
Differential regulation of Sox17 gene expression
Gene regulons in Sox17 expressing endodermal cells
Gene enrichment analysis for genes induced by excitotoxicity