{"id":154,"date":"2024-03-05T17:15:15","date_gmt":"2024-03-05T17:15:15","guid":{"rendered":"https:\/\/lab.dev.vanderbilt.edu\/younglab\/?page_id=154"},"modified":"2024-03-06T18:22:57","modified_gmt":"2024-03-06T18:22:57","slug":"publications","status":"publish","type":"page","link":"https:\/\/lab.dev.vanderbilt.edu\/younglab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"
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Selected Publications:<\/h3>\n<\/div>\n
    \n
  1. Egnatchik, R., Leamy, A., Sacco, S., Cheah, Y., Shiota, M., & Young, J. (2019). Glutamate\u2013oxaloacetate transaminase activity promotes palmitate lipotoxicity in rat hepatocytes by enhancing anaplerosis and citric acid cycle flux.\u00a0Journal of Biological Chemistry, 294<\/i>(9), 3081\u20133090.<\/li>\n
  2. Deja, S., Fu, X., Fletcher, J., Kucejova, B., Browning, J., Young, J., & Burgess, S. (2020). Simultaneous tracers and a unified model of positional and mass isotopomers for quantification of metabolic flux in liver.\u00a0Metabolic Engineering, 59<\/i>, 1\u201314.<\/li>\n
  3. Hasenour, C., Kennedy, A., Bednarski, T., Trenary, I., Eudy, B., Silva, R., Boyd, K., & Young, J. (2020). Vitamin E does not prevent Western diet-induced NASH progression and increases metabolic flux dysregulation in mice.\u00a0Journal of Lipid Research, 61<\/i>(5), 707\u2013721.<\/li>\n
  4. Cheah, Y., Xu, Y., Sacco, S., Babele, P., Zheng, A., Johnson, C., & Young, J. (2020). Systematic identification and elimination of flux bottlenecks in the aldehyde production pathway of\u00a0Synechococcus elongatus<\/i>\u00a0PCC 7942.\u00a0Metabolic Engineering<\/i>.<\/li>\n
  5. Potter, A., Butrico, C., Ford, C., Curry, J., Trenary, I., Tummarakota, S., Hendrix, A., Young, J., & Cassat, J. (2020). Host nutrient milieu drives an essential role for aspartate biosynthesis during invasive\u00a0Staphylococcus aureus<\/i>\u00a0infection.\u00a0Proceedings of the National Academy of Sciences, 117<\/i>(22), 12394\u201312401.<\/li>\n
  6. Hasenour, C., Rahim, M., & Young, J. (2020). In Vivo Estimates of Liver Metabolic Flux Assessed by 13C-Propionate and 13C-Lactate Are Impacted by Tracer Recycling and Equilibrium Assumptions.\u00a0Cell reports, 32<\/i>(5), 107986. C. C. Hughey, F. D. James, D. P. Bracy, E. P. Donahue,\u00a0J. D. Young<\/b>, B. Viollet, M. Foretz, D. H. Wasserman. Loss of hepatic AMP-activated protein kinase impedes the rate of glycogenolysis but not gluconeogenic fluxes in exercising mice.\u00a0Journal of Biological Chemistry<\/i>\u00a0292: 20125\u201320140, 2017.<\/li>\n
  7. B. Faubert, K. Y. Li, L. Cai, C. T. Hensley, J. Kim, L. G. Zacharias, C. Yang, Q. N. Do, S. Doucette, D. Burguete, H. Li, G. Huet, Q. Yuan, T. Wigal, Y. Butt, M. Ni, J. Torrealba, D. Oliver, R. E. Lenkinski, C. R. Malloy, J. W. Wachsmann,\u00a0J. D. Young<\/b>, K. Kernstine, R. J. DeBerardinis*. Lactate metabolism in human lung tumors.\u00a0Cell<\/i>\u00a0171:358\u2013371.e9, 2017.<\/li>\n
  8. N. Templeton, K. D. Smith, A. G. McAtee-Pereira, H. Dorai, M. J. Betenbaugh, S. E. Lang,\u00a0J. D. Young<\/b>*. Application of 13C flux analysis to identify high-productivity CHO metabolic phenotypes.\u00a0Metabolic Engineering<\/i>\u00a043:218\u2013225, 2017.<\/li>\n
  9. L. J. Jazmin, Y. Xu, Y. E. Cheah, A. O. Adebiyi, C. H. Johnson,\u00a0J. D. Young*<\/b>. Isotopically nonstationary 13C flux analysis of cyanobacterial isobutyraldehyde production.\u00a0Metabolic Engineering<\/i>\u00a042:9\u201318, 2017.<\/li>\n
  10. A. K. Leamy, C. M. Hasenour, R. A. Egnatchik, I. A. Trenary, C. Yao, G. J. Patti, M. Shiota,\u00a0J. D. Young<\/b>*. Knockdown of triglyceride synthesis does not enhance palmitate lipotoxicity or prevent oleate-mediated rescue in rat hepatocytes.\u00a0BBA\u2013Molecular and Cell Biology of Lipids<\/i>\u00a01861:1005\u20131014, 2016.<\/li>\n
  11. Y. M. Whang, S. I. Park, I. A. Trenary, R. A. Egnatchik, J. P. Fessel, J. Kaufman, D. P. Carbone,\u00a0J.D. Young<\/b>*. LKB1 deficiency enhances sensitivity to energetic stress induced by erlotinib treatment in non-small cell lung cancer (NSCLC) cells.\u00a0Oncogene<\/i>\u00a035:856\u2013866, 2016.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    Selected Publications: Egnatchik, R., Leamy, A., Sacco, S., Cheah, Y., Shiota, M., & Young, J. (2019). Glutamate\u2013oxaloacetate transaminase activity promotes palmitate lipotoxicity in rat hepatocytes by enhancing anaplerosis and citric acid cycle flux.\u00a0Journal of Biological Chemistry, 294(9), 3081\u20133090. Deja, S., Fu, X., Fletcher, J., Kucejova, B., Browning, J., Young, J., & Burgess, S. (2020). Simultaneous…<\/p>\n","protected":false},"author":465,"featured_media":0,"parent":0,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"tags":[],"class_list":["post-154","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/lab.dev.vanderbilt.edu\/younglab\/wp-json\/wp\/v2\/pages\/154","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lab.dev.vanderbilt.edu\/younglab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/lab.dev.vanderbilt.edu\/younglab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/lab.dev.vanderbilt.edu\/younglab\/wp-json\/wp\/v2\/users\/465"}],"replies":[{"embeddable":true,"href":"https:\/\/lab.dev.vanderbilt.edu\/younglab\/wp-json\/wp\/v2\/comments?post=154"}],"version-history":[{"count":3,"href":"https:\/\/lab.dev.vanderbilt.edu\/younglab\/wp-json\/wp\/v2\/pages\/154\/revisions"}],"predecessor-version":[{"id":258,"href":"https:\/\/lab.dev.vanderbilt.edu\/younglab\/wp-json\/wp\/v2\/pages\/154\/revisions\/258"}],"wp:attachment":[{"href":"https:\/\/lab.dev.vanderbilt.edu\/younglab\/wp-json\/wp\/v2\/media?parent=154"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lab.dev.vanderbilt.edu\/younglab\/wp-json\/wp\/v2\/tags?post=154"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}