{"id":15,"date":"2018-07-09T23:54:15","date_gmt":"2018-07-09T23:54:15","guid":{"rendered":"https:\/\/lab.dev.vanderbilt.edu\/steventownsend\/?page_id=15"},"modified":"2018-07-09T23:58:42","modified_gmt":"2018-07-09T23:58:42","slug":"publications","status":"publish","type":"page","link":"https:\/\/lab.dev.vanderbilt.edu\/steventownsend\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<div class=\"secmain\">\n<p><strong> Independent<\/strong><\/p>\n<p><strong><em>Under Review\/In Preparation<\/em><\/strong><\/p>\n<p>20. Kelly M. Craft and <strong>Steven D. Townsend<\/strong>. Chemical Biology. <em>IOBC. Invited Submission to the New Talent Issue. <strong>2018<\/strong>. <\/em><em>In Preparation.<\/em><\/p>\n<p>19. Kelly M. Craft, Jennifer A. Gaddy and <strong>Steven D. Townsend<\/strong>. <em>In Revision.<\/em><\/p>\n<p><strong><em>Published<\/em><\/strong><\/p>\n<p>18. Schuyler A. Chambers, Jenna M. DeSousa, Eric D. Huseman, and <strong>Steven D. Townsend*<\/strong>. The DARK Side of Total Synthesis: Strategies and Tactics in Psychoactive Drug Production. <em>ACS Chem. Neurosci. <\/em><strong>2018. <\/strong><strong>DOI:<\/strong> 10.1021\/acschemneuro.7b00528<\/p>\n<p><a href=\"https:\/\/s3.amazonaws.com\/vu-my\/wp-content\/uploads\/sites\/1308\/2014\/01\/12130211\/Picture1.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-998\" src=\"https:\/\/s3.amazonaws.com\/vu-my\/wp-content\/uploads\/sites\/1308\/2014\/01\/12130211\/Picture1.png\" alt=\"Picture1\" width=\"206\" height=\"154\" \/><\/a><\/p>\n<ul>\n<li><em>Invited submission<\/em><\/li>\n<\/ul>\n<p>17.\u00a0Dorothy L. Ackerman,# Kelly M. Craft,# Ryan S. Doster, J\u00f6rn-Hendrik Weitkamp, David M. Aronoff, Jennifer A. Gaddy, and<strong> Steven D. Townsend*<\/strong>.\u00a0Antimicrobial and Antibiofilm Activity of Human Milk Oligosaccharides Against <em>Streptococcus agalactiae, Staphylococcus aureus,<\/em> and <em>Acinetobacter baumannii<\/em>.\u00a0<em>ACS Infect. Dis.\u00a0<\/em><strong>2018.<\/strong> <strong>DOI<\/strong><strong>:<\/strong><em> 10.1021\/acsinfecdis.7b00183 <a href=\"https:\/\/s3.amazonaws.com\/vu-my\/wp-content\/uploads\/sites\/1308\/2014\/01\/27132401\/Extended-Scope-Graphical-Abstract-copy.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-975\" src=\"https:\/\/s3.amazonaws.com\/vu-my\/wp-content\/uploads\/sites\/1308\/2014\/01\/27132401\/Extended-Scope-Graphical-Abstract-copy.jpg\" alt=\"Extended Scope Graphical Abstract copy\" width=\"295\" height=\"221\" \/><\/a><\/em><\/p>\n<ul>\n<li><em># equal contribution<br \/>\n<\/em><\/li>\n<li>Most read article for December 2017!<\/li>\n<\/ul>\n<p>16. Kelly M. Craft and <strong>Steven D. Townsend*<\/strong>.\u00a0 The Human Milk Glycome as a Defense Against Infectious Diseases.\u00a0 <em>ACS Infect. Dis. <\/em><strong>2018. <\/strong><strong>DOI:<\/strong> 10.1021\/acsinfecdis.7b00209<\/p>\n<p><a href=\"https:\/\/s3.amazonaws.com\/vu-my\/wp-content\/uploads\/sites\/1308\/2014\/01\/13223836\/Slide1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-962\" src=\"https:\/\/s3.amazonaws.com\/vu-my\/wp-content\/uploads\/sites\/1308\/2014\/01\/13223836\/Slide1.jpg\" alt=\"Slide1\" width=\"489\" height=\"275\" \/><\/a><\/p>\n<p>15. Yong Guan and <strong>Steven D. Townsend*<\/strong>.\u00a0 Metal-Free Synthesis of Unsymmetrical Organoselenides and Selenoglycosides.\u00a0 <em>Org. Lett.<\/em> <strong>2017<\/strong><em>, <\/em>19, 5252-5255. <strong>DOI:<\/strong> 10.1021\/acs.orglett.7b02526<\/p>\n<p><a href=\"https:\/\/s3.amazonaws.com\/vu-my\/wp-content\/uploads\/sites\/1308\/2014\/01\/16163311\/YG.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-951\" src=\"https:\/\/s3.amazonaws.com\/vu-my\/wp-content\/uploads\/sites\/1308\/2014\/01\/16163311\/YG.jpg\" alt=\"YG\" width=\"388\" height=\"152\" \/><\/a><\/p>\n<p>14.\u00a0 D. Jamin Keith, Stefan A. Marasligiller,# Alexander W. Sasse,# and <strong>Steven D. Townsend*<\/strong>.\u00a0 One-Pot, Microwave-Assisted Conversion of Anomeric Nitrate-Esters. to Trichloroacetimidates. <em>J. Vis. Exp. <\/em><strong>2017.<\/strong> In Press.<strong><br \/>\n<\/strong><\/p>\n<ul>\n<li><em>Invited submission<\/em><\/li>\n<li># = undergraduate co-authors<\/li>\n<\/ul>\n<p>13. Dorothy L. Ackerman, Ryan S. Doster, J\u00f6rn-Hendrik Weitkamp, David M. Aronoff, Jennifer A. Gaddy, and <strong>Steven D. Townsend*<\/strong>.\u00a0 Human Milk Oligosaccharides Exhibit Antimicrobial and Anti-Biofilm Properties Against Group B Streptococcus.\u00a0 <em>ACS Infect. Dis. <\/em><strong>2<\/strong><cite><\/cite><strong><span class=\"citation_year\">017<\/span><\/strong>, <span class=\"citation_volume\">3,<\/span> 595-605. <strong>DOI:<\/strong> 10.1021\/acsinfecdis.7b00064<\/p>\n<p><a href=\"https:\/\/s3.amazonaws.com\/vu-my\/wp-content\/uploads\/sites\/1308\/2014\/01\/29165515\/GB1084_24hr_nooligo_011-copy.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-864\" src=\"https:\/\/s3.amazonaws.com\/vu-my\/wp-content\/uploads\/sites\/1308\/2014\/01\/29165515\/GB1084_24hr_nooligo_011-copy.png\" alt=\"GB1084_24hr_nooligo_011 copy\" width=\"174\" height=\"161\" \/><\/a><\/p>\n<ul>\n<li>Most read article for 2017!<\/li>\n<li>Cover Art for August 2017!<\/li>\n<li><a href=\"http:\/\/www.vanderbilt.edu\/vicb\/discovery_featured3.html\">Highlighted by Carol Rouzer &amp; the VICB<\/a>, <a href=\"https:\/\/in.style.yahoo.com\/breastmilk-may-ward-off-bacterial-123708364.html\">Yahoo!<\/a>,\u00a0<a href=\"https:\/\/www.sciencedaily.com\/releases\/2017\/08\/170820075008.htm\">ScienceDaily<\/a>,\u00a0<a href=\"http:\/\/www.infectioncontroltoday.com\/news\/2017\/08\/sugars-in-human-mothers-milk-are-new-class-of-antibacterial-agents.aspx\">Infection Control Today<\/a>,\u00a0<a href=\"http:\/\/www.contagionlive.com\/news\/sugars-in-breast-milk-found-to-have-antibacterial-properties?p=2\">Contagion Live<\/a>,\u00a0<a href=\"http:\/\/www.dailymail.co.uk\/health\/article-4808060\/Sugar-breast-milk-kill-superbugs.html\">DailyMail UK<\/a>,\u00a0<a href=\"https:\/\/phys.org\/news\/2017-08-sugars-human-mother-class-antibacterial.html\">Phys.Org<\/a>,\u00a0<a href=\"https:\/\/www.acs.org\/content\/acs\/en\/pressroom\/newsreleases\/2017\/august\/sugars-in-some-breast-milk-could-help-protect-babies-from-group-B-strep.html\">ACS-News \u00a0<\/a><\/li>\n<\/ul>\n<p>12.\u00a0 D. Jamin Keith and <strong>Steven D. Townsend*<\/strong>. \u00a0Direct, Microwave-Assisted Substitution of Anomeric Nitrate-Esters. <em>Carbohydr. Res.<\/em> <strong>2017<\/strong>, 442, 20-24.<\/p>\n<p><a href=\"https:\/\/s3.amazonaws.com\/vu-my\/wp-content\/uploads\/sites\/1308\/2014\/01\/21141926\/Graphical-Abstract1.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-807\" src=\"https:\/\/s3.amazonaws.com\/vu-my\/wp-content\/uploads\/sites\/1308\/2014\/01\/21141926\/Graphical-Abstract1.png\" alt=\"Graphical-Abstract\" width=\"276\" height=\"108\" \/><\/a><\/p>\n<p>11.\u00a0 Kelly M. Craft and <strong>Steven D. Townsend*<\/strong>.\u00a0 Synthesis of Lacto-<em>N<\/em>-Tetraose. <em>Carbohydr. Res.<\/em> <strong>2017<\/strong>, 440-441, 43-50.<\/p>\n<p><a href=\"https:\/\/s3.amazonaws.com\/vu-my\/wp-content\/uploads\/sites\/1308\/2014\/01\/09185211\/Graphical-Abstract.png\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-798 aligncenter\" src=\"https:\/\/s3.amazonaws.com\/vu-my\/wp-content\/uploads\/sites\/1308\/2014\/01\/09185211\/Graphical-Abstract.png\" alt=\"Graphical-Abstract\" width=\"736\" height=\"95\" \/><\/a><\/p>\n<p>10.\u00a0 Dorothy L. Ackerman, Kelly M. Craft, and <strong>Steven D. Townsend*<\/strong>.\u00a0 Infant Food Applications of Complex Carbohydrates:\u00a0 Structure, Synthesis, and Function.\u00a0 <em>Carbohydr. Res.<\/em> <strong>2017<\/strong>, 437, 16-27.<\/p>\n<p><a href=\"https:\/\/s3.amazonaws.com\/vu-my\/wp-content\/uploads\/sites\/1308\/2014\/01\/14164836\/1-s2.0-S0008621516303093-fx11.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-696\" src=\"https:\/\/s3.amazonaws.com\/vu-my\/wp-content\/uploads\/sites\/1308\/2014\/01\/14164836\/1-s2.0-S0008621516303093-fx11.jpg\" alt=\"1-s2.0-S0008621516303093-fx1\" width=\"486\" height=\"105\" \/><\/a><\/p>\n<p><strong>Mentored<\/strong><\/p>\n<p>9.\u00a0 Steven D. Townsend, Audrey G. Ross, Kai Liu, and Samuel J. Danishefsky*.\u00a0 Stereospecific Cis and Trans Ring Fusions Arising From Common Intermediates.\u00a0 <em>Proc. Natl. Acad. Sci. U.S.A. <\/em><strong>2014<\/strong>, 111(22), 7931-7935.<em><br \/>\n<\/em><\/p>\n<p>8.\u00a0 Steven D. Townsend and Gary A. Sulikowski*.\u00a0 Progress toward the Total Synthesis of Bielschowskysin.\u00a0 <em>Org. Lett.<\/em> <strong>2013<\/strong>, 15(19),\u00a05096-5098.<\/p>\n<p>7.\u00a0 Audrey G. Ross, Steven D. Townsend, and Samuel J. Danishefsky*.\u00a0 Halocycloalkenones as Diels-Alder Dienophiles.\u00a0 Applications to Generating Useful Structural Patterns.\u00a0 <em>J. Org. Chem<\/em>. <strong>2013<\/strong>, 78(1), 204-210. <em>Invited submission for the Robert Ireland Memorial Issue. <\/em><\/p>\n<p>6.\u00a0 Jianfeng Li, Suwei Dong, Steven D. Townsend, Thomas Dean, Thomas J. Gardella, and Samuel J. Danishefsky*.\u00a0 Chemistry as an Expanding Resource in Protein Science.\u00a0 Fully Synthetic and Fully Active Human Parathyroid Hormone-Related Protein (1-141). <em>Angew. Chem. Int. Ed<\/em>. <strong>2012<\/strong>, 51(49), 12263-12267.<\/p>\n<p>5.\u00a0 Ping Wang, Suwei Dong, John A. Brailsford, Karthik Iyer, Steven D. Townsend, Qiang Zhang, Ronald Henderickson, JaeHung Shieh, Malcolm A. S. Moore, and Samuel J. Danishefsky*.\u00a0 At Last: Erythropoietin as a Single Glycoform. <em>Angew. Chem. Int. Ed. <\/em><strong>2012<\/strong>, 51(46), 11576-11584.<\/p>\n<p>4.\u00a0 Steven D. Townsend, Xiangyang Wu, and Samuel J. Danishefsky*.\u00a0 Enhancing the Scope of the Diels-Alder Reaction through Isonitrile Chemistry: Emergence of a New Class of Acyl Activated Dienophiles. <em>J. Am. Chem. Soc<\/em>. <strong>2012<\/strong>, 134(25), 10659-10663.<\/p>\n<p>3.\u00a0 Steven D. Townsend, Zhongping Tan, Suwei Dong, Shiying Shang, John A. Brailsford, and Samuel J. Danishefsky*.\u00a0 Advances in Proline Ligation.\u00a0 <em>J. Am. Chem. Soc<\/em>. <strong>2012<\/strong>, 134(8), 3912-3916.<\/p>\n<p>2.\u00a0 Haibo Yu, Meng Wu, Steven D. Townsend, Beiyan Zou, Shunyou Long, J. Scott Daniels, Owen B. McManus, Min Li, Craig W. Lindsley, and Corey R. Hopkins*.\u00a0 Discovery, Synthesis, and Structure\u2013Activity Relationship of a Series of N-Aryl-bicyclo[2.2.1]heptane-2-carboxamides:\u00a0\u00a0 Characterization of ML213 as a Novel KCNQ2 and KCNQ4 Potassium Channel Opener. <em>ACS Chem. Neurosci.<\/em> <strong>2011<\/strong>, 2(10), 572\u2013577.<\/p>\n<p>1.\u00a0 Alexis S. Hammond, Alice L. Rodriguez, Steven D. Townsend, Colleen M. Niswender, Karen J. Gregory, Craig W. Lindsley, and P. Jeffrey Conn*. Discovery of a Novel Chemical Class of mGlu5 Allosteric Ligands with Distinct Modes of Pharmacology. <em>ACS Chem. Neurosci.<\/em> <strong>2010<\/strong>, 1(10), 702\u2013716.<\/p>\n<div><strong>NIH Molecular Libraries Program Probe Reports<\/strong><\/div>\n<div>\n<div>1. Yu, H.; Wu, M.; Hopkins, C. R.; Engers, J.; <span class=\"highlight selected\">Townsend<\/span>, S.; Lindsley, C.; McManus, O.B.; Li, M. A small molecule activator of KCNQ2 and KCNQ4 channels, 2011, Bookshelf ID: NBK121449.PMID: 23658954<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Independent Under Review\/In Preparation 20. Kelly M. Craft and Steven D. Townsend. Chemical Biology. IOBC. Invited Submission to the New Talent Issue. 2018. In Preparation. 19. Kelly M. Craft, Jennifer A. Gaddy and Steven D. Townsend. In Revision. Published 18. Schuyler A. Chambers, Jenna M. DeSousa, Eric D. Huseman, and Steven D. Townsend*. The DARK&#8230;<\/p>\n","protected":false},"author":112,"featured_media":0,"parent":0,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"tags":[],"class_list":["post-15","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/lab.dev.vanderbilt.edu\/steventownsend\/wp-json\/wp\/v2\/pages\/15","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lab.dev.vanderbilt.edu\/steventownsend\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/lab.dev.vanderbilt.edu\/steventownsend\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/lab.dev.vanderbilt.edu\/steventownsend\/wp-json\/wp\/v2\/users\/112"}],"replies":[{"embeddable":true,"href":"https:\/\/lab.dev.vanderbilt.edu\/steventownsend\/wp-json\/wp\/v2\/comments?post=15"}],"version-history":[{"count":1,"href":"https:\/\/lab.dev.vanderbilt.edu\/steventownsend\/wp-json\/wp\/v2\/pages\/15\/revisions"}],"predecessor-version":[{"id":16,"href":"https:\/\/lab.dev.vanderbilt.edu\/steventownsend\/wp-json\/wp\/v2\/pages\/15\/revisions\/16"}],"wp:attachment":[{"href":"https:\/\/lab.dev.vanderbilt.edu\/steventownsend\/wp-json\/wp\/v2\/media?parent=15"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lab.dev.vanderbilt.edu\/steventownsend\/wp-json\/wp\/v2\/tags?post=15"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}