Discovery and SAR of muscarinic receptor subtype 1 (M1) allosteric activators from a molecular libraries high throughput screen. Part 1: 2,5-dibenzyl-2H-pyrazolo[4,3-c]quinolin-3(5H)-ones as positive allosteric modulators
AUTHORS
Han
CChangho ,
Chatterjee
AArindam ,
Noetzel
MJMeredith J ,
Panarese
JDJoseph D ,
Smith
EEmery ,
Chase
PPeter ,
Hodder
PPeter ,
Niswender
CColleen ,
Conn
PJP Jeffrey ,
Lindsley
CWCraig W ,
Stauffer
SRShaun R .
Bioorganic & medicinal chemistry letters. 2014 11 18; 25(2).
384-8
- PMID: 25435150[PubMed].
ABSTRACT
Tags: 2014