Spatial localization of A2E in the retinal pigment epithelium.
Authors
Grey| Crouch| Koutalos| Schey| Ablonczy
AC| RK| Y| KL| Z
Angus C| Rosalie K| Yiannis| Kevin L| Zsolt
.
Investigative ophthalmology & visual science. 2011 6 ; 52(7).
3926-33
Investigative ophthalmology & visual science. 2011 6 ; 52(7).
3926-33
Abstract
Lipofuscin, a fluorescent lysosomal pigment made of lipophilic molecules, is associated with age-related pathophysiological processes in the retinal pigment epithelium (RPE). The best-characterized components of lipofuscin are A2E and its oxides, but a direct spatial correlation with lipofuscin has not previously been possible.