Posttranslational modifications of the bovine lens beaded filament proteins filensin and CP49.
Authors
Wang| Obidike| Schey
Z| JE| KL
Zhen| Joy E| Kevin L
.
Investigative ophthalmology & visual science. 2010 3 ; 51(3).
1565-74
Investigative ophthalmology & visual science. 2010 3 ; 51(3).
1565-74
Abstract
The lens beaded filament proteins filensin and CP49 are phosphorylated proteins that undergo proteolytic degradation with fiber cell age; however, the specific sites of modifications remain largely unknown. The purpose of this study was to identify posttranslational modifications (PTMs) in bovine lens beaded filament proteins.