MALDI Imaging Mass Spectrometry Spatially Maps Age-Related Deamidation and Truncation of Human Lens Aquaporin-0.
Authors
Wenke| Rose| Spraggins| Schey
JL| KL| JM| KL
Jamie L| Kristie L| Jeffrey M| Kevin L
.
Investigative ophthalmology & visual science. 2015 11 ; 56(12).
7398-405
Investigative ophthalmology & visual science. 2015 11 ; 56(12).
7398-405
Abstract
To spatially map human lens Aquaporin-0 (AQP0) protein modifications, including lipidation, truncation, and deamidation, from birth through middle age using matrix-assisted laser desorption ionization (MALDI) imaging mass spectrometry (IMS).