Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP)

Authors

Jain S Sanjay , Pei L Liming , Spraggins JM Jeffrey M , Angelo M Michael , Carson JP James P , Gehlenborg N Nils , Ginty F Fiona , Gonçalves JP Joana P , Hagood JS James S , Hickey JW John W , Kelleher NL Neil L , Laurent LC Louise C , Lin S Shin , Lin Y Yiing , Liu H Huiping , Naba A Alexandra , Nakayasu ES Ernesto S , Qian WJ Wei-Jun , Radtke A Andrea , Robson P Paul , Stockwell BR Brent R , Van de Plas R Raf , Vlachos IS Ioannis S , Zhou M Mowei , , Börner K Katy , Snyder MP Michael P .
Nature cell biology. 2023 7 19; 25(8).
1089-1100

Abstract

The Human BioMolecular Atlas Program (HuBMAP) aims to create a multi-scale spatial atlas of the healthy human body at single-cell resolution by applying advanced technologies and disseminating resources to the community. As the HuBMAP moves past its first phase, creating ontologies, protocols and pipelines, this Perspective introduces the production phase: the generation of reference spatial maps of functional tissue units across many organs from diverse populations and the creation of mapping tools and infrastructure to advance biomedical research.