Interlaboratory studies and initiatives developing standards for proteomics.
AUTHORS
Ivanov
ARAlexander R ,
Colangelo
CM Christopher M ,
Dufresne
CP Craig P ,
Friedman
DB David B ,
Lilley
KS Kathryn S ,
Mechtler
K Karl ,
Phinney
BS Brett S ,
Rose
KL Kristie L ,
Rudnick
PA Paul A ,
Searle
BC Brian C ,
Shaffer
SA Scott A ,
Weintraub
ST Susan T .
Proteomics. 2013 3 ; 13(6).
904-9
- PMCID: PMC3863631.
- NIHMSID: NIHMS528122
ABSTRACT
Proteomics is a rapidly transforming interdisciplinary field of research that embraces a diverse set of analytical approaches to tackle problems in fundamental and applied biology. This viewpoint article highlights the benefits of interlaboratory studies and standardization initiatives to enable investigators to address many of the challenges found in proteomics research. Among these initiatives, we discuss our efforts on a comprehensive performance standard for characterizing PTMs by MS that was recently developed by the Association of Biomolecular Resource Facilities (ABRF) Proteomics Standards Research Group (sPRG).