Race disparities in peptide profiles of North American and Kenyan Wilms tumor specimens.
AUTHORS
Libes
JMJaime M ,
Seeley
EH Erin H ,
Li
M Ming ,
Axt
JR Jason R ,
Pierce
J Janene ,
Correa
H Hernan ,
Newton
M Mark ,
Hansen
E Erik ,
Judd
A Audra ,
McDonald
H Hayes ,
Caprioli
RM Richard M ,
Naranjo
A Arlene ,
Huff
V Vicki ,
O'Neill
JA James A ,
Lovvorn
HN Harold N ,
.
Journal of the American College of Surgeons. 2014 4 ; 218(4).
707-20
- PMID: 24655859[PubMed].
- PMCID: PMC3964369.
- NIHMSID: NIHMS560369
ABSTRACT
Wilms tumor (WT) is the most common childhood kidney cancer worldwide and arises in children of black African ancestry with greater frequency and severity than other race groups. A biologic basis for this pediatric cancer disparity has not been previously determined. We hypothesized that unique molecular fingerprints might underlie the variable incidence and distinct disease characteristics of WT observed between race groups.
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