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Kupffer cell release of platelet activating factor drives dose limiting toxicities of nucleic acid nanocarriers


AUTHORS

Jackson MAMeredith A , Patel SSShrusti S , Yu FFang , Cottam MAMatthew A , Glass EBEvan B , Hoogenboezem ENElla N , Fletcher RBR Brock , Dollinger BRBryan R , Patil PPrarthana , Liu DDDanielle D , Kelly IBIsom B , Bedingfield SKSean K , King ARAllyson R , Miles RERachel E , Hasty AMAlyssa M , Giorgio TDTodd D , Duvall CLCraig L . Biomaterials. 2020 11 23; 268(). 120528

ABSTRACT