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Instrumentation | The McLean Group Laboratory for Structural Mass Spectrometry | Vanderbilt University Skip to main content

McLean Research Group Laboratory for Structural Mass Spectrometry

Instrumentation

McLean Research Group Instrumentation

Trapped Ion Mobility-Mass Spectrometer (timsTOF Pro 2, Bruker)

  • Electrospray Ionization (ESI)
  • Thermally-Assisted Electrospray Ionization (VIP-HESI, Bruker)
  • Liquid Chromatography (1290, Agilent)

Traveling Wave Structures for Lossless Ion Manipulation (TWSLIM) Ion Mobility-Mass Spectrometer Platform

MOBIE CE (MOBILion Systems) coupled to a 6546 QTOF (Agilent Technologies)

  • Thermally-Assisted Electrospray Ionization (ESI, Jet Stream, Agilent)
  • Liquid Chromatography (1290, Agilent)

Drift Tube Ion Mobility-Mass Spectrometer (6560-A, patched to Revision C, Agilent Technologies)

  • Thermally-Assisted Electrospray Ionization (ESI, Jet Stream)
  • Alternate Drift Gas Kit and Switching Manifold
  • In-Source Ion Activation Lens
  • High Resolution Demultiplexing (HRdm)
  • Liquid Chromatography (1290, Agilent)

Traveling Wave Ion Mobility-Mass Spectrometer (Synapt G2-S, Waters Corporation)

  • Electrospray Ionization (ESI)
  • Desorption ESI (DESI, Prosolia prototype)
  • Matrix-Assisted Laser Desorption Ionization (MALDI, Waters)
  • Electron Transfer Dissociation (ETD)
  • Liquid Chromatography
  • Supercriticial Fluid Chromatography (SFC, UPC2, Waters)

 

Legacy Instrumentation:

Voyager STR-DE MALDI-MS

  • MALDI
  • Linear TOF

MALDI/ESI drift tube IM-MS (Ionwerks and McLean Research Group)

  • MALDI (MSI capable)
  • ESI
  • Periodic focusing drift tube (15 cm)

Synapt G2 (Waters)

  • Electrospray Ionization (ESI)
  • Matrix-Assisted Laser Desorption Ionization (MALDI)
  • Atmospheric Solids Analysis Probe (ASAP)
  • Electron Transfer Dissociation (ETD)
  • Surface-Induced Dissociation (SID)
  • Gas Chromatography (GC)
  • Gel Permeation Chromatography (GPC)

Octoplex IM-MS (McLean Research Group)

  • Incl. 8-channel electrospray ionization (ESI)

ACQUITY UPC2 (Waters)

  • Supercritical fluid chromatography (SFC)
  • Normal- and reversed-phase

In addition, we have access to the resources of the Center for Innovative Technology.