Publications | Mchaourab Lab | Vanderbilt University

Principles of Alternating Access in Multidrug and Toxin Extrusion (MATE) Transporters

Dec. 2, 2021
Conserved binding site in the N-lobe of prokaryotic MATE transporters suggests a role for Na + in ion-coupled drug efflux

Dec. 2, 2021
Structure and assembly of CAV1 8S complexes revealed by single particle electron microscopy

Dec. 2, 2021
The Multidrug Transporter MdfA Deviates from the Canonical Model of Alternating Access of MFS Transporters

Oct. 16, 2020
ATP-dependent interactions of a cargo protein with the transmembrane domain of a polypeptide processing and secretion ABC transporter

Oct. 16, 2020
An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity

Oct. 16, 2020
A CLC-ec1 mutant reveals global conformational change and suggests a unifying mechanism for the CLC Cl -/H + transport cycle

Oct. 16, 2020
Supramolecular Approach to Electron Paramagnetic Resonance Distance Measurement of Spin-Labeled Proteins

Oct. 16, 2020
Cataract-linked γD-crystallin mutants have weak affinity to lens chaperones α-crystallins

Jul. 23, 2020
Cataract-linked γD-crystallin mutants have weak affinity to lens chaperones α-crystallins.

To test the hypothesis that α-crystallin chaperone activity plays a central role in maintenance of lens transparency, we investigated its interactions with γ-crystallin mutants that cause congenital cataract in mouse models. Although the two substitutions, I4F and V76D, stabilize a partially unfolded γD-crystallin intermediate, their affinities to α-crystallin are marginal… Read More

Jul. 23, 2020

Previous

1
2
3
4
5
6
7
8
9
…
13

Next