Circadian Clocks: Unexpected Biochemical Cogs.

Authors

Mori T Tetsuya , Mchaourab H Hassane , Johnson CH Carl Hirschie .
Current biology : CB. 2015 10 5; 25(19).
R842-4

Abstract

A circadian oscillation can be reconstituted in vitro from three proteins that cycles with a period of ∼ 24 h. Two recent studies provide surprising biochemical answers to why this remarkable oscillator has such a long time constant and how it can switch effortlessly between alternating enzymatic modes.