Vanderbilt University
Vanderbilt University
  • Our recent paper: Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter
  • Mchaourab lab - Overview
  • Sampling the conformational landscapes of transporters and receptors with AlphaFold2
  • Modeling Alternate Conformations with Alphafold2
  • Our work in Science!
  • Molecular Basis of Genetic Diseases program highlights
Vanderbilt University
  • Our recent paper: Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter
  • Mchaourab lab - Overview
  • Sampling the conformational landscapes of transporters and receptors with AlphaFold2
  • Modeling Alternate Conformations with Alphafold2
  • Our work in Science!
  • Molecular Basis of Genetic Diseases program highlights
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  • Temporal recording of mammalian development and precancer

    Temporal recording of mammalian development and precancer

    Apr. 15, 2025

  • Nonsynonymous single-nucleotide polymorphisms in the G6PC2 gene affect protein expression, enzyme activity, and fasting blood glucose

    Nonsynonymous single-nucleotide polymorphisms in the G6PC2 gene affect protein expression, enzyme activity, and fasting blood glucose

    Mar. 25, 2022

  • Sampling alternative conformational states of transporters and receptors with AlphaFold2

    Sampling alternative conformational states of transporters and receptors with AlphaFold2

    Mar. 25, 2022

  • Biophysical and functional properties of purified glucose-6-phosphatase catalytic subunit 1

    Biophysical and functional properties of purified glucose-6-phosphatase catalytic subunit 1

    Jan. 3, 2022

  • Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter

    Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter

    Dec. 21, 2021

  • Benchmark Test and Guidelines for DEER/PELDOR Experiments on Nitroxide-Labeled Biomolecules

    Benchmark Test and Guidelines for DEER/PELDOR Experiments on Nitroxide-Labeled Biomolecules

    Dec. 2, 2021

  • Protein functional dynamics from the rigorous global analysis of DEER data: Conditions, components, and conformations

    Protein functional dynamics from the rigorous global analysis of DEER data: Conditions, components, and conformations

    Dec. 2, 2021

  • Methodology for rigorous modeling of protein conformational changes by Rosetta using DEER distance restraints

    Methodology for rigorous modeling of protein conformational changes by Rosetta using DEER distance restraints

    Dec. 2, 2021

  • Psychomotor impairments and therapeutic implications revealed by a mutation associated with infantile Parkinsonism-Dystonia

    Psychomotor impairments and therapeutic implications revealed by a mutation associated with infantile Parkinsonism-Dystonia

    Dec. 2, 2021

  • AlphaFold2 predicts the inward-facing conformation of the multidrug transporter LmrP

    AlphaFold2 predicts the inward-facing conformation of the multidrug transporter LmrP

    Dec. 2, 2021

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Vanderbilt University
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Lab news

  • Our recent paper: Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter
  • Mchaourab lab – Overview
  • Sampling the conformational landscapes of transporters and receptors with AlphaFold2
  • Modeling Alternate Conformations with Alphafold2
  • Our work in Science!
  • Molecular Basis of Genetic Diseases program highlights

Hassane’s interview for the EPR newsletter

Molecular Basis of Genetic Diseases

Click here for Program website

https://lab.dev.vanderbilt.edu/mchaourab-lab/wp-content/uploads/sites/49/2020/02/MBGD_aboutvideo.mp4

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