Publications

Dos Santos Cristiane, Cambraia Amanda, Shrestha Shristi, Cutler Melanie, Cottam Matthew, Perkins Guy, Lev-Ram Varda, Roy Birbickram, Acree Christopher, Kim Keun-Young, Deerinck Thomas, Dean Danielle, Cartailler Jean-Philippe, MacDonald E, Hetzer Martin, Ellisman Mark, Arrojo E Drigo Rafael, Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity in mice Nat Commun. 2024 Oct 21;

Ma Zhibo, Lytle K, Chen Bob, Jyotsana Nidhi, Weiser Novak Sammy, Cho J, Caplan Leah, Ben-Levy Olivia, Neininger C, Burnette T, Trinh Q, Tan C B, Patterson A, Arrojo E Drigo Rafael, Giraddi R, Ramos Cynthia, Means L, Matsumoto Ichiro, Manor Uri, Mills C, Goldenring R, Lau S, Wahl M, DelGiorno E, Single-Cell Transcriptomics Reveals a Conserved Metaplasia Program in Pancreatic Injury Gastroenterology. 2022 Feb 16;

Dai Xiao-Qing, Camunas-Soler Joan, Briant J B, Dos Santos Theodore, Spigelman F, Walker M, Arrojo E Drigo Rafael, Bautista Austin, Jones C, Avrahami Dana, Lyon James, Nie Aifang, Smith Nancy, Zhang Yongneng, Johnson Janyne, Manning Fox E, Michelakis D, Light E, Kaestner H, Kim K, Rorsman Patrik, Stein W, Quake R, MacDonald E, Heterogenous impairment of α cell function in type 2 diabetes is linked to cell maturation state Cell Metab. 2022 Feb 1;

Nathan C Winn C, Cottam A, Bhanot Monica, Caslin L, Garcia N, Arrojo E Drigo Rafael, Hasty H, Weight Cycling Impairs Pancreatic Insulin Secretion but Does Not Perturb Whole-Body Insulin Action in Mice With Diet-Induced Obesity Diabetes. 2022 Nov 1;

Shrestha Shristi, Erikson Galina, Lyon James, Spigelman F, Bautista Austin, Manning Fox E, Dos Santos Cristiane, Shokhirev Maxim, Cartailler Jean-Philippe, Hetzer W, MacDonald E, Arrojo E Drigo Rafael, Aging compromises human islet beta cell function and identity by decreasing transcription factor activity and inducing ER stress Sci Adv. 2022 Oct 7;

Arrojo E Drigo Rafael, Probing β-Cell Biology in Space and Time Diabetes. 2021 Oct 7;

Krishna Shefali, Arrojo E Drigo Rafael, Capitanio S, Ramachandra Ranjan, Ellisman Mark, Hetzer W, Identification of long-lived proteins in the mitochondria reveals increased stability of the electron transport chain Dev Cell. 2021 Nov 8;

Arrojo e Drigo Rafael, Roy Birbickram, MacDonald Patrick, Molecular and functional profiling of human islets: from heterogeneity to human phenotypes Diabetologia. 2020 Sep 10 (63)

Arrojo e Drigo Rafael, Erickson Galina, Tyagi Swati, Capitanio Juliana, Lyon James, Spiegelman Aliya, Bautista Austin, Manning-Fox Jocelyn, Shokhriev Maxim, MacDonald Patrick, Hetzer Martin, Aging of human endocrine pancreatic cell types is heterogeneous and sex-specific bioRxiv. 2019 Jan

Arrojo e Drigo Rafael, Jacob Stefan, Garcia-Pietro Concha, Zheng Xiaofeng, Fukuda Masahiro, Thi Nhu Hoa Tran, Stelmashenko Olga, Martins Pecanha Flavia Leticia, Rodriguez-Diaz Rayner, Bushong Eric, Deerinck Thomas, Phan Sebastien, Ali Yusuf, Leibiger Ingo, Chua Minni, Boudier Thomas, Song Sang-Ho, Graf Martin, Augustine Geroge, Ellisman Mark, Berggren Per-Olof, Structural basis for delta cell paracrine regulation in pancreatic islets Nature Communications. 2019 Aug 10

Arrojo e Drigo Rafael, Lev-Ram Varda, Tyagi Swati, Ramachandra Ranjan, Deerinck Thomas, Bushong Eric, Phan Sebastien, Orphan Victoria, Lechene Claude, Ellisman Mark, Hetzer Martin, Age Mosaicism across Multiple Scales in Adult Tissues Cell Metabolism. 2019 Aug 6 (2)

Toyama Brandon, Arrojo e Drigo Rafael, Lev-Ram Varda, Ramachandra Ranjan, Deerinck Thomas, Lechene Claude, Ellisman Mark, Hetzer Martin, Visualization of long-lived proteins reveals age mosaicism within nuclei of postmitotic cells Journal of Cell Biology. 2018 Dec 14; 2 (218)

Diez Juan, Arrojo e Drigo Rafael, Zheng Xiaofeng, Stelmashenko Olga, Chua Minni, Rodriguez-Diaz Rayner, Fukuda Masahiro, Kohler Martin, Leibiger Ingo, Bo Bo Tun Sai, Ali Yusuf, Augustine George, Barathi Veluchamy, Berggren Per-Olof, Pancreatic Islet Blood Flow Dynamics in Primates Cell Reports. 2017 Aug 8; 20

Arrojo e Drigo Rafael, Ali Yusuf, Diez Juan, Kumar Srinivasan Dinesh, Berggren Per-Olof, Boehm Bernhard, New insights into the architecture of the islet of Langerhans: a focused cross-species assessment Diabetologia. 2015 Oct 1; 58 (10)