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We will determine if we can predict the ability of pyrvinium to reprogram the gastric mucosa using patient-derived pre-cancer organoids.  Also, we will initiate a clinical trial to evaluate the ability of a 2-week treatment with pyrvinium to reprogram metaplasia in a high-risk diverse population at Duke University in North Carolina. Read More

Amanda, welcome to our lab!  I bet you’re going to be an amazing addition. Welcome aboard!… Read More

Our new paper entitled “Oncogenic fatty acid metabolism rewires energy supply chain in gastric carcinogenesis” has been published in Gastroenterology! https://pubmed.ncbi.nlm.nih.gov/38272100/  … Read More

We have identified a unique monounsaturated fatty acid (MUFA) which fuels dysplastic cell hyperproliferation and survival. Stearoyl-CoA desaturase 1 (SCD1), a catalytic enzyme in the synthesis of unsaturated fatty acids, is specifically upregulated in the transitioning area from metaplasia to dysplasia and strongly expressed in human gastric patient tissues with… Read More

We welcome Anavi, a new undergraduate in the lab! She is becoming a molecular biology expert!… Read More

Halee successfully passed her oral qualifying exam! Great Job!… Read More

We welcome Suyeon, a new postdoc in the lab! She will study SPEM cell plasticity and evolution with cell biology concepts. Read More

epithelialbiology.org  … Read More

Foundation Awards Two $100,000 Grants to Advance Gastric Cancer Research  … Read More