{"id":100,"date":"2018-05-30T15:44:34","date_gmt":"2018-05-30T15:44:34","guid":{"rendered":"https:\/\/lab.dev.vanderbilt.edu\/carneiro-lab\/projects\/"},"modified":"2018-06-13T15:47:35","modified_gmt":"2018-06-13T15:47:35","slug":"projects","status":"publish","type":"page","link":"https:\/\/lab.dev.vanderbilt.edu\/carneiro-lab\/projects\/","title":{"rendered":"Projects"},"content":{"rendered":"

\"Workflow.jpg\"<\/p>\n

 <\/p>\n

Elucidate physical interactions between SERT and\u00a0aVb3 and delineate the functional consequences of disruption of the SERT\/aVb3 complex.<\/strong><\/p>\n

Here we utilize biochemical techniques in both mouse brain preparations and heterologous expression systems to identify\u00a0the discrete structural changes that modulate transporter function by direct integrin binding.\u00a0These studies will reveal if the molecular binding of integrin beta3 is necessary and sufficient for appropriate SERT function in the brain.<\/p>\n

Background:<\/p>\n

24769.pdf<\/a><\/p>\n

JCI0833374.pdf<\/a><\/p>\n

www.ncbi.nlm.nih.gov\/pubmed\/21774491<\/a><\/p>\n

www.ncbi.nlm.nih.gov\/pubmed\/16722239<\/a><\/p>\n

www.ncbi.nlm.nih.gov\/pubmed\/20846430\u00a0<\/a><\/p>\n

www.ncbi.nlm.nih.gov\/pubmed\/12482823<\/a><\/p>\n

www.ncbi.nlm.nih.gov\/pubmed\/19630800<\/a><\/p>\n

www.ncbi.nlm.nih.gov\/pubmed\/19630802<\/a><\/p>\n

www.ncbi.nlm.nih.gov\/pubmed\/18772455<\/a><\/p>\n

International Students<\/h3>\n

Students from abroad can join the Interdisciplinary Graduate\u00a0Program<\/a>.<\/p>\n

Brasil<\/h3>\n

O departamento de farmacologia abre as suas portas para alunos de doutorado e p\u00f3s-doutorado interessados em desenvolver projetos de pesquisa em Vanderbilt. Mais informa\u00e7\u00f5es entre em contato: ana.carneiro@vanderbilt.edu<\/a>.\u00a0Estudantes Brasileiros podem entrar para o programa de p\u00f3s-gradua\u00e7\u00e3o da Universidade de Vanderbilt atrav\u00e9s do programa Ci\u00eancia sem Fronteiras ou atrav\u00e9s do programa Vanderbilt International Scholar. Para maiores informa\u00e7\u00f5es entre no site do\u00a0BRET\u00a0ou e-mail ana.carneiro@vanderbilt.edu<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"

  Elucidate physical interactions between SERT and\u00a0aVb3 and delineate the functional consequences of disruption of the SERT\/aVb3 complex. Here we utilize biochemical techniques in both mouse brain preparations and heterologous expression systems to identify\u00a0the discrete structural changes that modulate transporter function by direct integrin binding.\u00a0These studies will reveal if the molecular binding of integrin beta3…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"tags":[],"class_list":["post-100","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/lab.dev.vanderbilt.edu\/carneiro-lab\/wp-json\/wp\/v2\/pages\/100","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lab.dev.vanderbilt.edu\/carneiro-lab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/lab.dev.vanderbilt.edu\/carneiro-lab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/lab.dev.vanderbilt.edu\/carneiro-lab\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/lab.dev.vanderbilt.edu\/carneiro-lab\/wp-json\/wp\/v2\/comments?post=100"}],"version-history":[{"count":5,"href":"https:\/\/lab.dev.vanderbilt.edu\/carneiro-lab\/wp-json\/wp\/v2\/pages\/100\/revisions"}],"predecessor-version":[{"id":150,"href":"https:\/\/lab.dev.vanderbilt.edu\/carneiro-lab\/wp-json\/wp\/v2\/pages\/100\/revisions\/150"}],"wp:attachment":[{"href":"https:\/\/lab.dev.vanderbilt.edu\/carneiro-lab\/wp-json\/wp\/v2\/media?parent=100"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lab.dev.vanderbilt.edu\/carneiro-lab\/wp-json\/wp\/v2\/tags?post=100"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}